Best Biotech Podcasts (2024)

1
Getting Tumors to Say “Eat Me” 25:08

2h ago25:08

25:08

While existing immunotherapies have changed cancer care, there are several types of cancer where they have limited or no efficacy. Pheast Therapeutics is addressing that by looking to macrophages, part of the innate immune system. These white blood cells gobble up pathogens, cancer cells, and other foreign substances. Certain tumors, though, can ev…

1
Ep. 81: Biomedical Engineering: The Future of Research? 32:16

1h ago32:16

32:16

As researchers continue to look for new ways to test therapeutics in vitro, the field of biomedical engineering is offering new microphysiological systems that can reduce the need for animal models. Hear from Jeffrey Borenstein, Director of the Biomedical Engineering Centre at Draper, as he explains how it works, ways to expedite its access, and th…

1
Anticipating Future Limiters of Biotech Applications - Joe Damond 41:19

2h ago41:19

41:19

n this episode, Dr. Kevin Folta speaks with Joe Damond about the rapidly evolving landscape of life sciences, particularly focusing on gene and cell therapies. They discuss the exciting advancements in medical technology, the economic challenges associated with developing new therapies, and the implications for healthcare systems and patient access…

1
Anticipating Future Limiters of Biotech Applications - Joe Damond 41:19

3h ago41:19

41:19

n this episode, Dr. Kevin Folta speaks with Joe Damond about the rapidly evolving landscape of life sciences, particularly focusing on gene and cell therapies. They discuss the exciting advancements in medical technology, the economic challenges associated with developing new therapies, and the implications for healthcare systems and patient access…

1
The future of extreme climate events 33:08

2h ago33:08

33:08

Climate change authority Noah Diffenbaugh says that the effects of climate change are no longer theoretical but apparent in everyday, tangible ways. Still, he says, it is not too late to better understand the effects of climate change, to mitigate them through reductions in greenhouse gas emissions and other measures, and to adapt how we live in th…

1
Targeting the Dark Matter of the Genome to Treat Diseases 32:33

23h ago32:33

32:33

About 98 percent of the the human genome consists of non-protein coding regions known as the “dark genome.” Once derided as “junk DNA,” these regions are increasingly understood to play a critical role in the regulation of the genome and offer a novel means of targeting diseases. Haya Therapeutics is exploring long non-coding RNAs as potential ther…

1
Apeel: A Solution to Food Waste - Jennny Du 28:19

5d ago28:19

28:19

In this episode of the Talking Biotech podcast, Kevin Folta interviews Jenny Du, co-founder and senior vice president of operations at Apeel, a company focused on reducing food waste through innovative post-harvest technology. They discuss the significant issue of food waste, particularly in fresh produce, and how Apeel's products work to extend th…

1
Apeel: A Solution to Food Waste - Jennny Du 28:19

5d ago28:19

28:19

In this episode of the Talking Biotech podcast, Kevin Folta interviews Jenny Du, co-founder and senior vice president of operations at Apeel, a company focused on reducing food waste through innovative post-harvest technology. They discuss the significant issue of food waste, particularly in fresh produce, and how Apeel's products work to extend th…

1
The future of climate projection 29:05

6d ago29:05

29:05

Climate modeler Aditi Sheshadri says that while weather forecasting and climate projection are based on similar science, they are very different disciplines. Forecasting is about looking at next week, while projection is about looking at the next century. Sheshadri tells host Russ Altman how new data and techniques, like low-cost high-altitude ball…

1
Using AI to Discover Small Molecule Alternatives to Biologics 31:33

8d ago31:33

31:33

One of the promises of AI is to redefine what’s possible by enabling the discovery of compounds that exist in a much larger chemical space than scientists have previously been able to explore. Deepcure is using AI and physics to discover small molecule therapies that can bind to difficult to target proteins. We spoke to Kfir Schreiber, co-founder a…

1
Ep167: Leslie Williams on transfer RNA therapies 1:11:28

8d ago1:11:28

1:11:28

Leslie Williams, CEO of Boston-based hC Bioscience, on developing transfer RNA therapies.By Timmerman Report

1
Ep. 80: Diversity in Veterinary Medicine 44:55

9d ago44:55

44:55

I am joined by Raphael (Ralph) Malbrue, Director & Attending Veterinarian, Center for Comparative Medicine, University of Virginia; and Christina (Winnie) Winnicker, Executive Director for Laboratory Animal Medicine for Charles River. Both bring a fresh perspective to the questions of how to improve diversity in veterinary medicine, how to inform n…

1
Best of: Computation cracks cold cases 30:50

13d ago30:50

30:50

Halloween may be behind us in the US but here at The Future of Everything we’re not quite done with spooky season. If you’re pairing your trick-or-treat haul with some scary movies, we invite you to revisit with us a conversation Russ had with Lawrence Wein a couple years ago about the work he’s doing in forensic genetic genealogy to crack cold cas…

1
A BET on a Novel Approach to Treat Autoimmune Conditions 24:40

15d ago24:40

24:40

The BET family of proteins regulates gene expression. Their overexpression has been implicated in both cancer and inflammatory diseases. Vyne Therapeutics is developing oral and topical BET inhibitors that treat inflammatory conditions ranging from rheumatoid arthritis to the skin condition vitiligo. We spoke to Vyne CEO David Domzalski and Vyne Ch…

1
The future of autonomous vehicles 29:23

20d ago29:23

29:23

Returning guest Marco Pavone is an expert in autonomous robotic systems, such as self-driving cars and autonomous space robots. He says that there have been major advances since his last appearance on the show seven years ago, mostly driven by leaps in artificial intelligence. He tells host Russ Altman all about the challenges and progress of auton…

1
Cell Therapies that Can Do a Solid for People with Cancer 51:49

27d ago51:49

51:49

In August, the U.S. Food and Drug Administration approved Adaptimmune’s Tecelra, the first engineered cell therapy to treat a solid tumor. The T cell receptor gene therapy is approved to treat synovial sarcoma, a rare soft tissue cancer that most often affects young adults. We spoke to Adrian Rawcliffe, CEO of Adaptimmune, about the approval, how T…

1
Trees that Survive Citrus Greening - Gary England 50:50

26d ago50:50

50:50

Citrus greening disease or HLB has severely impacted Florida citrus production. And while many solutions have been proposed, there is interest in a number of trees that have shown to not show symptoms of the disease. This week's episode discusses the disease with retired extension specialist Gary England as he evaluates "survivor" trees. These tree…

1
Trees that Survive Citrus Greening - Gary England 50:50

1M ago50:50

50:50

Citrus greening disease or HLB has severely impacted Florida citrus production. And while many solutions have been proposed, there is interest in a number of trees that have shown to not show symptoms of the disease. This week's episode discusses the disease with retired extension specialist Gary England as he evaluates "survivor" trees. These tree…

1
The future of ultrafast electronics 36:37

27d ago36:37

36:37

Physicist Matthias Kling studies photons and the things science can do with ultrafast pulses of X-rays. These pulses last just attoseconds – a billionth of a billionth of a second, Kling says. He uses them to create slo-mo “movies” of electrons moving through materials like those used in batteries and solar cells. The gained knowledge could reshape…

1
Going to Extremes to Discover New Drugs 31:38

1M ago31:38

31:38

Hibernation is not just a matter of deep sleep. Animals that hibernate are able to do so without suffering damage to tissue and muscle. Understanding the biology of hibernation can unlock potential insights into obesity, heart attack and stroke, muscle atrophy, neuroprotection, and longevity. Fauna Bio is studying genomic data from so-called "extre…

1
Ep166: Chris Garcia on Engineering Protein Drugs for Cancer, Autoimmunity 1:03:35

29d ago1:03:35

1:03:35

Chris Garcia, professor at Stanford University and co-founder of several biotech startups, on using protein engineering to advance new treatments for cancer and autoimmune diseases.By Timmerman Report

1
Ep. 79: Painting a Picture of Hope to Treat PACS2 53:44

1M ago53:44

53:44

Piotr Kosla, founder of the PACS2 Research Foundation, joins us to discuss his personal motivation to develop the first treatment for Development and Epileptic Encephalopathy 66 (PACS2 Syndrome), how cell painting assays are being used to repurpose a treatment for this condition, what the future holds for research in this area, and how you can help…

1
The New Face of Anti-Ag Pseudoscience - Vance Crowe 47:18

1M ago47:18

47:18

In this conversation, Dr. Kevin Folta and Vance Crowe discuss the evolving landscape of agriculture communication, the rise of pseudoscience, and the cultural shifts affecting public trust in science. Vance shares his journey from working at Monsanto to founding Legacy Interviews, emphasizing the importance of capturing personal stories. They explo…

1
The New Face of Anti-Ag Pseudoscience - Vance Crowe 47:18

1M ago47:18

47:18

In this conversation, Dr. Kevin Folta and Vance Crowe discuss the evolving landscape of agriculture communication, the rise of pseudoscience, and the cultural shifts affecting public trust in science. Vance shares his journey from working at Monsanto to founding Legacy Interviews, emphasizing the importance of capturing personal stories. They explo…

1
Best of: An innovative polling model can move us beyond political polarization 28:00

1M ago28:00

28:00

We’re just weeks away from a national election, and in our polarized society, we all know it can be difficult to find and create spaces for thoughtful policy discussions. A couple of years ago, James Fishkin, a professor of communication at Stanford, joined the podcast. He talked about a system called deliberative polling that can serve as a model …

1
Targeting Senescent Cells to Treat Aging-Related Diseases 31:44

1M ago31:44

31:44

Senescent cells, ones that no longer divide but are metabolically active, are associated with aging. They are also implicated in a broad range of aging-related diseases including cancer, diabetes, and neurodegenerative conditions. In the case of cancer, these cells can help protect tumors from a person’s immune system. Immorta Bio is seeking to add…

1
Biotech Enhancement of Protein in World Staple Crops - Dr. Ling Li 28:45

2M ago28:45

28:45

Protein is essential for normal human development and physiology, yet is a significant global deficiency. World food staple crops like rice, wheat, cassava, and potato have relatively protein levels, yet constitute a significant portion of calories consumed. Dr. Ling Li of Mississippi State University has identified that overexpression of a gene ca…

1
Biotech Enhancement of Protein in World Staple Crops - Dr. Ling Li 28:45

1M ago28:45

28:45

Protein is essential for normal human development and physiology, yet is a significant global deficiency. World food staple crops like rice, wheat, cassava, and potato have relatively protein levels, yet constitute a significant portion of calories consumed. Dr. Ling Li of Mississippi State University has identified that overexpression of a gene ca…

1
The future of GPS 31:21

1M ago31:21

31:21

Astronautics professor Grace Gao is an authority on the Global Positioning System. GPS has long been key to navigation on Earth, she says, but science is now shifting its focus outward to the frontiers of space. Gao is working on a GPS-like system for the Moon. To keep costs low, this lunar positioning system will leverage Earth-based satellites co…

1
Bringing Cellular Diversity into Sharper Focus 30:35

1M ago30:35

30:35

From cell to cell within a given tissue, variability exists. Single-cell sequencing technologies from 10X Genomics is helping researchers and drug developers understand cellular diversity in tissue once thought to be made up of homogenous populations. This has the potential to lead to new understandings of diseases, open up new targets for drug dev…

1
Ep. 78: Starting Over After Cancer 23:58

1M ago23:58

23:58

Lisa Sharp, Project Coordinator for Charles River, joins us to discuss her COVID lockdown experience. Right at the beginning of the pandemic, just weeks apart, both she and her husband were diagnosed with cancer. Sadly, he didn't make it. While Lisa and their daughter faced the worst, she decided to make big changes to her life and career. Listen n…

1
The future of female athletic health 30:38

2M ago30:38

30:38

Sports medicine physician Emily Kraus knows a lot about the health challenges of female athletes. Women face far more ACL tears and bone stress injuries than men, for instance, and excessive training or poor nutrition can also delay puberty and affect menstruation. These differences are vastly understudied, she says. To close the gap, Kraus initiat…

1
Ep165: Zach Hornby on Tackling Cancer Drug Resistance 1:02:45

2M ago1:02:45

1:02:45

Zach Hornby, CEO of San Diego-based Boundless Bio, on tackling cancer drug resistance.By Timmerman Report

1
Developing Cancer Therapies for When Damage Control Goes Awry 18:09

2M ago18:09

18:09

The DDR pathway plays a critical role in repairing DNA damage in healthy cells that would otherwise cause mutations or cell death. When this pathway is altered and becomes unable to repair this damage, mutated cells can grow out of control and become cancerous. They can also be more resistant to standard chemotherapies and radiation. Aprea Therapeu…

1
Delivering the Goods 36:06

2M ago36:06

36:06

Nearly 70 percent of patients with chronic conditions fail to take their medicines as prescribed. This can lead to poor outcomes and greater healthcare costs. Vivani Medical, which has developed implantable drug delivery technology, said it can provide steady drug release for up to six months with a single implant. This not only can address the pro…

1
Best of: How to fight climate change 27:50

2M ago27:50

27:50

Today, we’re bringing you a best-of from our archive of over 250 episodes. We’re all aware that the consequences of climate change range from rising sea levels, to drought, wildfires, economic disruption and the displacement of populations. We’re seeing and living through many of these effects, but is there hope for managing additional risk? A coup…

1
Ep. 77: Ophirex: Biting Back 1:01:34

2M ago1:01:34

1:01:34

Imagine you’re exploring the great outdoors when, out of nowhere, you feel the fangs of a snake – a poisonous snake – breaking through your skin. Medical care is nowhere in sight, so you’re left with the terrifying prospect of venom slowly infecting your body’s critical functions. This is the reality that roughly five million people face annually. …

1
The future of skin longevity 29:35

2M ago29:35

29:35

Taken any selfies lately? Dermatologist Zakia Rahman studies both the science of healthy skin and the effects of the exponential increase in skin images on self-esteem. As a result, skin health is linked to mental health, she says. It’s not about vanity, it’s about vitality, Rahman tells host Russ Altman on this episode of Stanford Engineering’s Th…

1
Swimming in the New Oil 22:26

2M ago22:26

22:26

One of the key obstacles to developing new drugs and diagnostics is the lack of access to longitudinal biological and clinical patient data. Culmination Bio, a spin-out of Intermountain Health, is building the largest patient data platform with more than 40 years of de-identified patient electronic health records and biospecimen data. We spoke to L…

1
The future of AI at work 32:59

2M ago32:59

32:59

Arvind Karunakaran studies the intersections of work, AI, and organizational behavior. He says AI can enhance speed and productivity in the short run, yet degrade skills over time. But it is in organizational power dynamics where AI has had its most marked impact, he says, telling host Russ Altman about situations in law firms where AI has fostered…

1
Ep164: Ted Love and Alan Anderson on Raising the Bar for Sickle Cell Disease Patients 56:39

2M ago56:39

56:39

Ted Love, chairman of BIO, and Dr. Alan Anderson, executive director of Sickle Forward, on how to improve quality of life for sickle cell disease patients around the world.By Timmerman Report

1
Does This Drug Represent “A Paradigm Shift for Small Molecule Drug Development?” 28:01

2M ago28:01

28:01

NAMPT is a critical enzyme that regulates how cells use energy. It can also play an important role in the ability of cancer cells to survive, grow, and spread. While it’s been recognized as a potential target to treat certain cancers, developing NAMPT inhibitors have been challenging because they can disrupt energy metabolism in healthy cells. Reme…

1
Ep. 76: Multi-Organ Chip Systems 31:31

2M ago31:31

31:31

I am joined by Dr. Kacey Ronaldson-Bouchard from Columbia University, who is an expert on linking organs on a chip together to form models of human systems. Can these models replace animals? Can they save time and money in drug development and safety testing? Find out now when you listen to this podcast!…

1
Best of: Better ways to build an airplane 26:28

3M ago26:28

26:28

We want to wish our listeners in the states a happy Labor Day weekend. We hope, wherever you are, you’re taking some time to savor the last bit of summer. After a couple months full of travel and news about the airplane industry, we can’t help wondering — are there better ways to build airplanes? Our previous guest, Ilan Kroo, an expert in aeronaut…

1
Exploring the Promise and Peril of CRISPR 57:36

3M ago57:36

57:36

The emergence of CRISPR, a powerful tool for gene editing, promises to correct devastating genetic diseases, but it also raises concerns about how it will be used and who will make those decisions. Neal Baer, in his new book “The Promise and Peril of CRISPR,” brings together a series of essays by bioethicists, geneticists, and others who explore et…

1
The future of Russia and Ukraine 32:21

3M ago32:21

32:21

Political scientist Kathryn Stoner is the Director of the Center on Democracy, Development and the Rule of Law (CDDRL) at Stanford and an authority on Russian/Ukrainian politics. She says views on the current war depend on which side someone is on: Many Russians and their leader Vladimir Putin say Ukrainians are Russians and have been since the 10t…

1
Transforming Protein Engineering with Generative AI 35:47

3M ago35:47

35:47

Speeding Protein Engineering with Whether it’s the development of new biotherapeutics, or replacing hydrocarbons from their role in industrial manufacturing, engineering proteins suited for a task is a time consuming and expensive process. Cradle Bio has developed generative AI technology to accelerate protein engineering by reducing the number of …

1
The GMO Tree You Never Heard About - Dr. Chris Dardick, USDA/ARS 34:14

3M ago34:14

34:14

We regularly discuss a small suite of commercial crops that have been genetically enhanced with transgenes. However, one additional genotype was transformed long ago, and approved for use in the USA, Canada and EU-- but nobody talks about it much. It is the plum resistant to plum pox virus (PPV), a devastating virus of stonefruits. While rare in th…

1
The GMO Tree You Never Heard About - Dr. Chris Dardick, USDA/ARS 34:14

3M ago34:14

34:14

We regularly discuss a small suite of commercial crops that have been genetically enhanced with transgenes. However, one additional genotype was transformed long ago, and approved for use in the USA, Canada and EU-- but nobody talks about it much. It is the plum resistant to plum pox virus (PPV), a devastating virus of stonefruits. While rare in th…

1
The future of educational technology 30:02

3M ago30:02

30:02

Dan Schwartz is a cognitive psychologist and dean of the Stanford Graduate School of Education. He says that artificial intelligence is a different beast, but he is optimistic about its future in education. “It’s going to change stuff. It’s really an exciting time,” he says. Schwartz imagines a world not where AI is the teacher, but where human stu…

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