Best KCAS Podcasts (2025)

1
Patient-Centric Sampling: Beyond the Clinic and What it Means for Bioanalysis 1:35:35

25d ago1:35:35

1:35:35

Dom and John, the hosts of “The Weekly Bioanalysis”, recently returned from EBF in Barcelona where there was a session on Patient-centric Microsampling, which both of them founnd fascinating. This inspired both of them to decide it was high time to revisit this part of our industry. In spite of a few infamous setbacks caused by the dishonesty of a …

1
The Role of Flow in Drug Autoimmune Indication Research 1:00:41

1M ago1:00:41

1:00:41

In episode 16 of The Conversational Flow podcast, hosts Brian Wile and Adam Cotty are joined by Allie Greenplate and Ayman Rezk to explore “The Role of Flow in Drug Autoimmune Indication Research.” The discussion delves into the surge in pharmaceutical R&D for immune and autoimmune indications, highlighting the influence of oncology treatments in s…

1
Small Molecule LC-MS Development and Evolving Approach to ADC Payloads 1:32:24

2M ago1:32:24

1:32:24

In episode 84 of “The Weekly Bioanalysis”, our special guest, Bryan Parmentier, joins Dom and John to discuss his background and current role at KCAS Bio, offering insights into the field of small molecule method development. He delves into the typical challenges encountered when working with LC-MS analytes, and how the evolving role of LC-MS conti…

1
Fantastic Fluorophores and Where to Find Them (w/ Kelly Lundsten) 1:05:35

2M ago1:05:35

1:05:35

In this exciting 15th episode of The Conversational Flow podcast, titled "Fantastic Fluorophores and Where to Find Them," hosts Brian Wile and Adam Cotty from KCAS Bio are joined by special guest Kelly Lundsten from FluoroFinder. Together, they dive into the fascinating world of spectral flow cytometry, exploring key questions such as whether spect…

1
Recap of the European Bioanalysis Forum Open Symposium 1:17:51

3M ago1:17:51

1:17:51

The 2024 tradeshow and conference season is finally coming to a close for the pharmaceutical and biotech industry, and our road-weary traveling hosts, Dom and John have returned from their final event, the 2024 European Bioanalysis Forum (EBF) Open Symposium in Barcelona, Spain. EBF was founded in 2006 at the initiative of 12 pharmaceutical compani…

1
Modifying Flow Cytometry Panels: the “Backbone” of Flow Cytometry 50:27

3M ago50:27

50:27

A flow cytometry backbone panel is a set of antibodies that can be used as a starting point for identifying cell types, and then supplemented with additional markers. On the most recent episode of “The Conversational Flow”, our hosts, Brian and Adam, spend some time together as they answer the questions of “What is a backbone panel?”, “What type of…

1
Conference Season 2024: KCAS Bio’s Upcoming Exhibitions & Presentations 1:32:03

4M ago1:32:03

1:32:03

It’s conference season! This is a busy, busy time of the year for the entire industry, when everyone comes together from around the world to share, listen and discuss the changes and advancements taking place in the business and science of the pharma and biotech space. During this episode of “The Weekly Bioanalysis”, our hosts, Dom and John, go ove…

1
Low Content Analysis: When a smaller panel is better than a larger one 1:04:14

4M ago1:04:14

1:04:14

During the most recent episode of “The Conversational Flow” podcast, our hosts Brian and Adam talk about those times when a smaller panel might be desirable over a larger panel. To dive deep into this discussion and really analyze all the angles of these questions, the guys have invited a special guest to join them – Amrutesh Puranik, PhD. Amrutesh…

1
GLP-1 Analogue Bioanalysis: The Value of Complimentary Technologies 1:09:35

5M ago1:09:35

1:09:35

After such a great response to our recent episode on the topic, our hosts, Dom and John, revisit the topic of GLP-1 Analogue development and the role bioanalysis plays in this relatively new and popular topic. In the words of John, “Everyone else is talking about this; why shouldn’t we?” And wow, do they have a lot to say about it on this second pa…

1
High Content Analysis: Finding Needles in a Growing Haystack 1:03:05

5M ago1:03:05

1:03:05

In the 12th episode of “The Conversational Flow” podcast, Brian and Adam welcome two special guests – Sean Burke of Denovo Software and Ryan Brinkman of Dotmatics – who join them to discuss the answers to a number of specific questions about High Content Analysis: How can we manage and derive insight from higher complexity panels? How can this be s…

1
The Rapid Evolution of PCR Assays with Special Guest, Carrie Vyhlidal 1:22:46

6M ago1:22:46

1:22:46

Our hosts, Dom and John, are excited to welcome special guest, Carrie Vyhlidal, to discuss the topic of the 80th episode of “The Weekly Bioanalysis” podcast – The Rapid Evolution of PCR Assays. PCR (or Polymerase Chain Reaction) is like a copying machine for DNA. Scientists have found ways to measure the copies being made throughout the reactions, …

1
Going Global with Spectral Flow Cytometry - US, EU and Now Australia 1:06:10

6M ago1:06:10

1:06:10

During this special episode of "The Conversational Flow" our hosts, Brian and Adam, welcome two guests: John Bucksath, CEO of KCAS Bio, and Stefan Cross, CEO of Crux Laboratories. These two guests discuss the elements and advantages of their organizations' new partnership between KCAS' US and European locations and Crux's location in Melbourne, Aus…

1
One & Done Therapies: The Landscape of Gene Therapy for Conditions 1:20:09

7M ago1:20:09

1:20:09

The most recent episode of "The Weekly Bioanalysis" podcast is all about genes today! The topic was originally inspired by an article entitled "The Coming of Age of One-and-Done Therapies" which jumped out to both of our hosts, Dom and John, and had been on the back burner for a while for them to discuss. With KCAS Bio housing entire departments sp…

1
Instrument Comparison: Some Instruments are More Equal than Others 55:01

7M ago55:01

55:01

When it comes to flow cytometry instrumentation, there are a number of things that can be different. You may have different types of lasers, you might have a different path for the laser to follow to get to the detector, you can have different actual detectors, different filters in front of those detectors, not to mention the varying sensitivities …

1
Offering Global Services: Latest News from Lyon and Melbourne 1:22:04

8M ago1:22:04

1:22:04

Dom has been globe-trotting lately, and he has come back to report in on his adventures with John, as they discuss our global services here at KCAS Bio. They talk about the updates and the latest news from Lyon and the rollout of our collaboration with Crux Laboratories in Melbourne. Most notable was Dom’s trip to Lyon and some of the excitement he…

1
Batch Effects, Controls, and Considerations for Longitudinal Studies 1:04:56

8M ago1:04:56

1:04:56

Let’s face it - nobody likes batch effects (unless it has to do with cookies, but that’s for another podcast). In episode #9 of “The Conversational Flow”, Brian and Adam talk about Batch Effects which is when you're having changes in the study that are not necessarily related to the scientific variables of the study – and what that might mean you w…

1
Non-GLP Studies from Early PK to Readiness for GLP Tox Studies 1:30:42

9M ago1:30:42

1:30:42

Dom and John welcome special guests, Habibi Goudarzi and Rochelle Burke to episode #77 of "The Weekly Bioanalysis", where they discuss the progression of bioanalytical needs for non-GLP Studies, from Early PK to readiness for GLP Tox Studies. These specialists from the KCAS Bio team begin with an introduction to all things non-GLP and LC-MS. From t…

1
Receptor Occupancy Testing in Clinical Trials 45:36

9M ago45:36

45:36

For episode #8 of “The Conversational Flow” podcast, Brian and Adam spend the time discussing Receptor Occupancy Testing in Clinical Trials. Receptor occupancy (RO) assays are important in clinical trials because they provide valuable information about a drug’s binding characteristics and mechanism of action. Our hosts begin by outlining the genera…

1
GLP-1 Analogues: Blockbuster Drugs - Applications & Challenges 1:25:52

10M ago1:25:52

1:25:52

For episode #76 of "The Weekly Bioanalysis", Dom and John talk about the popular topic of GLP-1 Analogues - these series of recent blockbuster drugs with multiple applications, as well as some of their bioanalytical challenges. First, the guys go over a little bit of the mechanism of action of GLP-1's, then some of the rules around them and their i…

1
The Current State of Receptor Occupancy Validation 1:00:34

10M ago1:00:34

1:00:34

For episode #7 of “The Conversational Flow”, Brian and Adam invite David Ambrose to join them as they continue their conversation about Receptor Occupancy assays. There are so many unique considerations around an RO assay and with any flow cytometry assay, the precision of that assay is important. Our hosts discuss the biggest differentiators when …

1
Rebranding KCAS Bio: Next Steps to an Integrated Future 1:03:05

11M ago1:03:05

1:03:05

CEO of KCAS Bio, John Bucksath, joins Dom and John for a special 75th episode of “The Weekly Bioanalysis” podcast, and he is absolutely delighted to use the special episode to talk about the recent rebrand of KCAS to KCAS Bio! Mr Bucksath and our hosts discuss the reason the rebrand came about, the process our organization took, and some of the ini…

1
Receptor Occupancy: Deceptively Simple Questions 38:05

11M ago38:05

38:05

The newest episode of “The Conversational Flow” has Brian and Adam talking about the concepts around Receptor Occupancy and all the deceptively simple questions people often have about them, as well as the important but sometimes difficult answers to those questions. They talk about the biology of receptors and the few different "classes" associate…

1
Addressing the Needs of Rare Diseases: Challenges & Trends 1:13:14

12M ago1:13:14

1:13:14

During this episode of “The Weekly Bioanalysis”, Dom and John talk about addressing the needs of rare diseases - some challenges and industry trends they’ve watched take place, and they are joined by guest, Lindsay Rutherford, who has her own personal experience with rare disease and how it can impact lives. As a bioanalytical provider, KCAS Bio of…

1
What Is Cell Sorting and What Role Does It Play in Bioanalysis? 44:13

1y ago44:13

44:13

During this newest episode of “The Conversational Flow”, Brian and Adam discuss cell sorting and the pivotal role it plays in molecular biology applications – enabling researchers to isolate specific cell populations from complex mixtures, as well as a number of other benefits. Our hosts dive into the importance of cell sorting, the evolution of th…

1
The Parallel Evolution of the Bioanalytical Industry and KCAS 1:10:40

1y ago1:10:40

1:10:40

To kick off the first episode of “The Weekly Bioanalysis” in 2024, Dom and John unveil some fun new things happening at KCAS, by talking about the parallel evolution of the bioanalytical industry and KCAS. Our hosts go way back – almost to “square one” (discussing “What is bioanalysis?” and “How has bioanalysis changed over the years?”. They take a…

1
What Makes Spectral Flow so Significant? 46:15

1y ago46:15

46:15

For the 4th episode of “The Conversational Flow” podcast, Brian and Adam discuss spectral flow; something really near and dear to their hearts. This is a topic both of our hosts have been genuinely interested in since they really became aware of it, at which time they immediately began pushing to bring the instrumentation to KCAS. While they have h…

1
Introduction to Scientific Advisor Team and Recap of 2023 1:16:54

1y ago1:16:54

1:16:54

For the final episode of “The Weekly Bioanalysis” in 2023, Dom and John invited KCAS’s scientific advisory team to join them, as we thought that as we are coming to the end of the year, it might be a good opportunity to introduce a few members of the scientific advisory team who may be involved in some greater capacity with the podcast going forwar…

1
How do You Validate a Flow Cytometry Assay? 43:47

1y ago43:47

43:47

There are a number of different guidances for Flow Cytometric Assay Validation, so for episode #3 of “The Conversational Flow” podcast, Brian and Adam go into great detail on how we perform validations at KCAS, and under what context we do so – and why. In this episode, the guys break down the different types of validation and the various levels of…

1
Drug Development and Where Bioanalytical Fits In 1:17:50

1y ago1:17:50

1:17:50

Dom and John have been doing this for a long time (for over 70 episodes now, to be exact), but they felt it might be a good idea to jump back to the very beginning and discuss the overarching concept of the Drug Development process and where it is that Bioanalysis fits in. This is somewhat of a response to a recent listener request, but we also fee…

1
How Sample Collection Impacts Flow Cytometry 56:02

1+ y ago56:02

56:02

For our second episode of “The Conversational Flow” podcast, Brian and Adam felt that the best topic to discuss was that of sample collection, sample processing and the important role it plays in Flow Cytometry analysis. This is an often discussed topic – What is the best way to collect and process samples – and it really comes down how you plan to…

1
Episode 210: Episode 210 Brinson talks LORD PREPARE A TABLE & post KCA, prayers for Israel, Jarred Allstar & more. 30:52

1+ y ago30:52

30:52

Episode 210 Brinson talks LORD PREPARE A TABLE & post KCA, prayers for Israel, Jarred Allstar & more.

1
Why Does Flow Cytometry Need Its Own Podcast? 40:51

1+ y ago40:51

40:51

Flow cytometry is a technique used to detect and measure physical and physiological characteristics of a population of cells or particles. Tens of thousands of cells can be quickly examined and the data gathered is processed by a computer. Uses of flow cytometry can included determination of Cellular characteristics and function, biomarker detectio…

1
Looking Forward to the 2023 Autumn Conference Season 1:08:46

1+ y ago1:08:46

1:08:46

It is that time of year once again... the Fall Conference Season! Every industry has its own set of important trade shows and meetings, but for the Pharma, biotech and bioanalytical industries, these conferences are an opportunity for the planet's leading experts to get together and share the newest ways to heal the world. With October almost upon …

1
Episode 209: Episode 209 Brinson talks being honored at the KCAs, #Ahsoka , and more. Tune in now #godchaserz #CHH 30:50

1+ y ago30:50

30:50

Episode 209 Brinson talks being honored at the KCAs, #Ahsoka , and more. Tune in now #godchaserz #CHH

1
The Evolving World of Antibody-Drug Conjugates and How KCAS Can Help 1:20:46

1+ y ago1:20:46

1:20:46

Starting off with a description of Antibody Drug Conjugates (or ADCs, for short), Dom and John dive into this field of the industry and discuss the ways these services have changed over time and even how they've changed recently. They review the role of ADCs in meeting some of the unmet medical needs in oncology and the way they're changing the eff…

1
Molecular Cell & Gene Therapy, with Special Guest Carrie Vyhlidal, PhD 1:27:32

1+ y ago1:27:32

1:27:32

Special guest Carrie Vyhlidal, PhD of KCAS joins John and Dom in the 68th episode of "The Weekly Bioanalysis" to discuss the ways molecular cell & gene therapy services has evolved and why their role will likely become more and more important to the world of bioanalytical drug development in the future. They discuss everything from the history of C…

1
Evolution of PK Modalities & the Impact on Regulations 1:05:42

2y ago1:05:42

1:05:42

In the world of bioanalysis, pharmacokinetics is a key step in the process of measuring and identifying elements of the drug. It is a baseline for sample analysis, and in episode 67 of "The Weekly Bioanalysis", Dom and John discuss the history and evolution drug and pharmacokinetic modalities and the impact on regulations. "The Weekly Bioanalysis" …

1
Episode 208: Brinson Interviews Multi-talented Musician and Homeschooling Mom, Under5ive, on The GodChaserz Podcast, Discussing Her Passions for Music, Natural Foods, and Preparing the Next Generation ... 32:11

2y ago32:11

32:11

On this episode of The GodChaserz Podcast, we have a special guest who goes by the name Under5ive. She's a multi-talented musician, a health enthusiast, a homeschooling mom, and an expert in money management. Under5ive shares her journey in the music industry and how she's been able to balance her passion for music with her other interests, includi…

1
Recent Advances in Hybrid LC-MS/MS (w/ guests Dawn Dufield and Barry Jones) 1:48:25

2y ago1:48:25

1:48:25

Special guests Dawn Duffield, PhD of KCAS and Barry Jones, PhD of Crinetics join John and Dom in the 66th episode of "The Weekly Bioanalysis" to discuss the ways Hybrid LC-MS/MS has advanced in recent years and how the technology has gone from "new" and somewhat obscure to much more mainstream as a leading option for program success within the phar…

1
Episode 207: . Plus, New Music. 32:10

2y ago32:10

32:10

GodChaserzDoc.com

1
The Role Early Non-clinical Bioanalysis Plays in Your Project 1:18:25

2y ago1:18:25

1:18:25

Dom and John discuss the role early non-clinical bio analysis plays in your project, why it is important, how it has changed over the years, and what might be next for this growing part of the industry. "The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutic…

1
Episode 206: Brinson interviews Alcott about his new album, love for CHH, and the power of prayer. #Superbowl Champs Kansas City #Chief new unreleased song by Cstraights 32:11

2y ago32:11

32:11

Brinson interviews Alcott about his new album, love for CHH, and the power of prayer. #Superbowl Champs Kansas City #Chief & a new unreleased song by Cstraight

1
Episode 205: Brinson talks Lebron / #LeGoat breaking records, 10Things4CHH.com, Tim Nu & More. 30:35

2y ago30:35

30:35

Brinson talks Lebron / #LeGoat breaking records, 10Things4CHH.com, Tim Nu & More. Patreon.com/GodChaserz Playlist1. Thre - Fisherman2. Monster Tarver - God Energy3. Boy Wonder - " Big Tymin ft. Von Won & Brinson4. Oatmeal - Drop ft. Mitch Darrell5. Rigz - ENcore ft. Brinson6. ReadyWriter - Higher Heights 7. CStraight - Been Wondering ft. ReadyWrite…

1
A Review of 2022's "Fierce 15" and What it Means for 2023 1:23:57

2y ago1:23:57

1:23:57

In what is becoming an annual tradition here on “The Weekly Bioanalysis” podcast, Dom and John take a bit of time to take a look back at 2022’s Fierce 15 (the annual selected list of impressively performing companies across the biotech world, highlighting a broad range of teams, leaders and science, as selected by the Fierce Biotech group). In addi…

1
Episode 204: Best of 2022 Episode w/ guest Sketch the Journalist & ReadyWriter. We talk best CHH albums, CHH Verses, and TV shows/movies of 2022 #BestOf2022 #BestOf 1:25:34

2y ago1:25:34

1:25:34

Best of 2022 Episode w/ guest Sketch the Journalist & ReadyWriter. We talk best CHH albums, CHH Verses, and TV shows/movies of 2022 #BestOf2022 #BestOf

1
A Look Back at 2022 While Looking Ahead to 2023 at KCAS 1:26:00

2y ago1:26:00

1:26:00

It has been an extremely transformative year for KCAS in 2022. As we approach the beginning of 2023, Dom and John take a moment during episode #63 to look back at all the changes and evolutionary growth that has transpired around the organization (and around the world, as we now have multiple European footprints as well as US locations). They go in…

1
Episode 203: Brinson interviews Eric Boston head of FiveTwenty Collective. They Talk CHH, Faith, music Tech and more. #Music #MusicTech #CHH 30:48

2y ago30:48

30:48

Brinson interviews Eric Boston head of FiveTwenty Collective. They Talk CHH, Faith, music Tech and more. #Music #MusicTech #CHH

1
An Introduction to Active Biomarkers, with Special Guests John Bucksath and Marc Essodaigui 1:17:40

2y ago1:17:40

1:17:40

Special guests John Bucksath, CEO of KCAS in Olathe, KS and Marc Essodaigui, General Manager of Active Biomarkers in Lyon, France, join Dom and John this week as they introduce our listeners to Active Biomarkers – the most recent acquisition of KCAS in the European space. The gentlemen discuss a brief history of Active Biomarkers, the path to their…

1
The 2022 Pharma/Biopharma Trade Show & Conference Season 1:20:23

2+ y ago1:20:23

1:20:23

Every year, beginning in late August, with the summer over and everyone settling back into a normal routine, the entire industry begins preparing itself for the conference and trade show season. These events serve as a source for new business in some cases, of course, but they also serve as an opportunity for like-minded scientists and industry lea…

1
Clinical Sample Kitting: Personal Touch Drives Success 1:00:08

2+ y ago1:00:08

1:00:08

Clinical Sample Kitting and Sample Storage have played vital roles in the pharmaceutical and Biopharmaceutical industry for decades, but KCAS began offering the services in the early 1990s in response to shortcomings observed in the collection techniques in trials where we were providing bioanalytical support. During episode #60 of "The Weekly Bioa…

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