Saving Lives Podcast: Critical Care w/eddyjoemd is a podcast that reviews evidence-based strategies to care for the critically ill patient in the Intensive Care Unit and other topics in Medicine. It is hosted by Eddy Joe Gutierrez, MD, a board-certified critical care physician. In each episode, Dr. Gutierrez discusses the latest research and best practices in Intensive Care Medicine. He also shares his own insights and experiences as an Intensivist/Critical Care physician. The podcast is des ...
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Normosol-R vs. Lactated Ringer’s: Do Buffered Crystalloids Impact ICU Outcomes?
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8:14In this episode of the Saving Lives Podcast, we break down a randomized trial from CHEST (2025) comparing Normosol-R vs. Lactated Ringer’s in critically ill adults. Learn whether acetate/gluconate-buffered fluids offer advantages over lactate-buffered solutions regarding acid-base balance, kidney function, and mortality. Tune in to hear how this st…
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Lactated Ringer’s vs. 0.9% Saline in Sepsis: Does Fluid Choice Affect Survival?
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11:29In this episode of the Saving Lives Podcast, we review a 2025 study from Critical Care Medicine comparing lactated Ringer’s and normal saline for initial fluid resuscitation in sepsis-induced hypotension. The findings suggest that LR may improve survival and increase hospital-free days compared to NS, supporting current guidelines favoring balanced…
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Cardiogenic Shock: Insights on Mortality and Management
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8:00In this episode of the Saving Lives Podcast, we review a nationwide study on cardiogenic shock in general ICUs, recently published in the European Heart Journal: Acute Cardiovascular Care. Discover why non-ischemic heart failure now leads cardiogenic shock admissions, which patient groups face the highest mortality, and how early ICU intervention c…
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Reducing ICU Delirium: The Role of Sleep Interventions
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8:05In this episode of the Saving Lives Podcast, we explore a systematic review and meta-analysis from the Journal of Critical Care on sleep interventions in ICU patients. We learn about the effectiveness of pharmacologic and non-pharmacologic strategies in reducing delirium and discover how improving sleep could transform critical care outcomes. The V…
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Sepsis Order Sets: Potentially Enhancing Outcomes and Reducing Costs in Care
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7:38In this episode of the Saving Lives Podcast, we dive into the latest research from CHEST, exploring how sepsis order sets can improve care value. Learn about the impact of these sets on reducing mortality, lowering hospital costs, and their role in streamlining sepsis management. Discover why order sets can be a game-changer for hospitals and socie…
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Continuous Glucose Monitoring: Is It the Future of ICU Glycemic Control?
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8:44In this episode of the Saving Lives Podcast, Eddy Joe breaks down a study comparing continuous glucose monitoring systems (CGMS) to conventional point-of-care monitoring in ICU patients. Learn how CGMS improves glycemic control, reduces variability, and eases nursing workloads, even without reducing mortality. The Vasopressor & Inotrope HandbookI h…
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Propofol Infusion Syndrome: A Rare but Deadly Complication in ICU Sedation
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10:06In this episode of The Saving Lives Podcast, we explore Propofol Infusion Syndrome (PRIS), looking at this complication's incidence, laboratory, and clinical manifestations. Hat tip to the authors.The Vasopressor & Inotrope HandbookI have written "The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals," a must-read for …
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Hyperdynamic LV Function in Septic Patients: Does It Matter?
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7:18In this episode of The Saving Lives Podcast, we dive into a compelling study from the Annals of Intensive Care, exploring the prevalence and impact of hyperdynamic left ventricular systolic function in septic patients. Unpacking the findings, we discuss how this condition influences mortality rates and what it means for clinical practice in intensi…
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Advance Directives in the ICU: Challenges and Challenges
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7:21In this episode of The Saving Lives Podcast, we delve into the intricate subject of advance directives in the intensive care setting. Titled "Deciphering the Complex World of Advance Directives in ICU Care: Challenges and Solutions," the episode explores the historical background, implementation challenges, and the impact of advance directives on p…
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Does Left Atrial Appendage Closure Worsen Postoperative Atrial Fibrillation Risk in Cardiac Surgery?
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9:05In this episode, we discuss recent findings on the potential risks of left atrial appendage closure (LAAC) in cardiac surgery patients without prior atrial fibrillation. The study highlights an increased risk of new-onset postoperative AF and prolonged hospital stays without clear benefits in mortality or stroke prevention. The Vasopressor & Inotro…
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Severe Tricuspid Regurgitation Treatment: Transcatheter Tricuspid-Valve Replacement (TRISCEND II)
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9:23In this episode of the Saving Lives Podcast, Eddy Joe explores the TRISCEND II trial’s groundbreaking findings on transcatheter tricuspid valve replacement (TTVR) for severe tricuspid regurgitation. Learn about the quality-of-life improvements, procedural risks, and future directions for this innovative therapy. The Vasopressor & Inotrope HandbookI…
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Dexmedetomidine in Septic Shock: DecatSepsis Trial
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10:35In this episode of the Saving Lives Podcast, we dive into the DecatSepsis trial, exploring the role of dexmedetomidine in reducing mortality and managing septic shock. Discover how this sedative could help mitigate the harmful effects of the hyperadrenergic state in septic patients. The Vasopressor & Inotrope HandbookI have written "The Vasopressor…
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Minocycline: A New Hope in Delirium Prevention for Critically Ill Patients?
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10:05In this episode of the Saving Lives Podcast, we discuss a recent randomized controlled trial exploring the use of minocycline to prevent delirium in critically ill patients. The study reveals that minocycline may significantly reduce delirium incidence and hospital mortality, offering a promising new pharmacologic approach. The Vasopressor & Inotro…
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DKA Management: Balanced Electrolyte Solutions vs. Saline
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9:07In this episode of the Saving Lives Podcast, Eddy Joe delves into the latest research comparing balanced electrolyte solutions to 0.9% saline for treating diabetic ketoacidosis (DKA). Discover how BES could potentially revolutionize DKA management by speeding up recovery and reducing complications. Tune in for an in-depth analysis of the study and …
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Optimizing Organ Procurement: Managing Brain-Dead Donors in the ICU
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8:29In this episode, Eddy Joe delves into the intensive care management of brain-dead donors, based on a recent article from Intensive Care Medicine. Learn about hemodynamic support, endocrine treatment, and respiratory management strategies to optimize organ procurement. Tune in for an in-depth discussion on improving donor organ viability while maint…
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Vasopressin vs. Norepinephrine in Post Cardiac Surgery-Related Vasoplegia
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8:13In this episode of the Saving Lives Podcast, we examine a groundbreaking 2017 study comparing vasopressin and norepinephrine for treating vasoplegic shock after cardiac surgery. We explore the study's compelling results, how vasopressin outperformed norepinephrine in reducing severe complications, and the potential implications for clinical practic…
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Frailty Assessment in Critically Ill Older Adults: Implications for ICU Care
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6:47In this episode of the Saving Lives Podcast, we discuss the comprehensive review of frailty assessment tools in critically ill older adults. Learn about the Clinical Frailty Scale and how these tools can influence clinical practice and patient outcomes. Tune in for insights on improving care for the elderly in ICU settings. The Vasopressor & Inotro…
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The Vasopressor & Inotrope HandbookI have written "The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals," a must-read for anyone caring for critically ill patients (check out the reviews)! You have several options to get a physical copy. Amazon: https://amzn.to/47qJZe1 (Affiliate Link)Signed & Personalized Copy: …
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CPR Duration and Outcomes in In-Hospital Cardiac Arrest
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6:44What are the outcomes in patients who suffer in-hospital cardiac arrest based on the duration of the code? This podcast episode covers a retrospective cohort study that analyzed this. The Vasopressor & Inotrope HandbookI have written "The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals," a must-read for anyone caring…
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Artificial Intelligence and Mechanical Ventilation
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5:46In this episode, we explore a groundbreaking study on the cost-effectiveness of artificial intelligence (AI) in managing mechanically ventilated ICU patients. Discover how AI can improve patient outcomes, reduce hospital stays, and enhance decision-making in critical care settings. Tune in to learn about AI's potential to revolutionize ICU care and…
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In this episode of The Saving Lives Podcast, we explore the innovative MitraClip system, a less invasive treatment for mitral regurgitation. The discussion covers the device's evolution, its impact on patient outcomes, and the challenges and complications associated with its use. The Vasopressor & Inotrope HandbookI have written "The Vasopressor & …
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Rethinking Physical Restraints: Unveiling ICU Practices and Patient Care
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7:39In this episode of The Saving Lives Podcast, we delve into the compelling findings of a recent review on the adverse effects of physical restraint use in ICUs. We discuss the paradoxical nature of restraints, designed for patient safety but linked to significant complications, including skin injuries, delirium, PTSD, and more. Understanding the lim…
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New 2024 Guidelines: Corticosteroids in Sepsis, ARDS, and CAP
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6:51This episode delves into the 2024 update on corticosteroid guidelines for critically ill patients with sepsis, ARDS, and community-acquired pneumonia. We break down the recommendations, evidence, and clinical implications of this crucial guidance for healthcare providers. The Vasopressor & Inotrope Handbook: Amazon Affiliate Link (I will ea…
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Exploring the Potential of Therapeutic Plasma Exchange in Sepsis
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5:53In this episode, we delve into the groundbreaking study "Influence of therapeutic plasma exchange treatment on short-term mortality of critically ill adult patients with sepsis-induced organ dysfunction." We explore how Therapeutic Plasma Exchange (TPE) could revolutionize the treatment of sepsis, a condition notoriously difficult to manage. The ep…
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Integrating Palliative Care in the ICU: Enhancing Quality of Life
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10:01In this episode of The Saving Lives Podcast, "Integrating Palliative Care in the ICU: Enhancing Quality of Life," host EddyJoe discusses the article 'Palliative Care in Intensive Care' from 'Intensive Care Medicine.' The episode examines how palliative care improves patient quality of life and reduces ICU stays, highlighting its role beyond end-of-…
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The Impact of Microcirculation Assessment in ICU Shock Patients: Insights from the DAMIS Trial
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5:15In this episode, we delve into the groundbreaking DAMIS trial, exploring the impact of sublingual microcirculation assessment on treatment decisions for ICU patients with shock. We discuss the methodology, findings, and implications of this extensive multicenter study, offering insights into how real-time microcirculatory data influences clinical o…
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Should We Go Searching for Asymptomatic Catheter-Related Thrombosis?
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6:52The Vasopressor & Inotrope Handbook: Amazon Affiliate Link (I will earn an extra small commission) and Signed Copies. Show Notes: eddyjoemd.com/asymptomatic-catheter-related-thrombosis/ Explore the often-overlooked issue of asymptomatic catheter-related thrombosis (CRT) in ICU patients on The Saving Lives Podcast. This episode delves into a reveali…
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Haloperidol in ICU Delirium: Insights from the EuRIDICE Trial
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4:55This episode delves into the pivotal EuRIDICE randomized clinical trial published in Critical Care in 2023. This episode provides an in-depth analysis of the trial's findings on using haloperidol in managing delirium among critically ill adults in the ICU. We'll explore the implications of these results for clinicians and the broader healthcare com…
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Show Notes: https://eddyjoemd.com/book/ This Podcast was Editing Using Descript: https://www.descript.com?lmref=BGOxjQ TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/ Discount code: EDDYJOEMD25
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Direct (DL) vs Video Laryngoscopy (VL) for Intubation? DEVICE Trial
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13:42In this podcast I break down the DEVICE trial looking at using video laryngoscopy (VL) or direct laryngoscopy (DL) for intubation.Show Notes: https://eddyjoemd.com/vl-dl-intubation/This Video was Editing Using Descript: https://www.descript.com?lmref=BGOxjQ TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/ Discount code: EDDYJ…
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Aortic Pulsatility Index (API): Optimizing Cardiogenic Shock Management
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17:23First of all, I apologize for the bad audio. This episode was lost until my buddy Haney Mallemat (@criticalcarenow) saved it. Aortic pulsatility index (API) is a hemodynamic measurement being studied to predict clinical outcomes in heart failure & cardiogenic shock. Show Notes: https://eddyjoemd.com/aortic-pulsatility-index/ TrueLearn Link: https…
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IV Thiamine: Can it Help Critically Ill Septic Shock Patients?
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22:57IV Thiamine may be helpful to improve the outcomes of critically ill (ICU) patients who have sepsis or septic shock. Show Notes: https://eddyjoemd.com/iv-thiamine TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/ Discount code: EDDYJOEMD25 Although great care has been taken to ensure that the information in this podcast are accura…
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Hydrocortisone for Severe Community-Acquired Pneumonia (CAP)
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9:53Show Notes: https://eddyjoemd.com/hydrocortisone-cap/ In this episode of the podcast, I discuss a new study that found that hydrocortisone can save lives in patients with severe community-acquired pneumonia (CAP). I discuss the findings and what they mean for the treatment of CAP. In addition I also discuss the risks and benefits of using hydrocort…
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Show Notes: https://eddyjoemd.com/methylene-blue-septic-shock/Link to Lactic Acid Post: https://eddyjoemd.com/lactic-acid-sepsis/ In this episode, we discuss the use of methylene blue as a potential treatment for septic shock. We explore the science behind how methylene blue can help improve circulation and reduce inflammation in patients experienc…
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In this episode, Dr. Eddy Joe explores the crucial role of Vitamin B12, hydroxocobalamin, can be potentially used in septic shock. He discusses the indications using evidence based medicine of how hydroxocobalamin can potentially be helpful in septic shock and how Vitamin B12 can help in treating this life-threatening condition. This informative an…
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Appreciating Our Nurses: The Role of the ICU Physician
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14:49Show Notes: eddyjoemd.com/appreciating-nurses/ TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/Discount code: EDDYJOEMD25 Citation: Vincent JL, Boulanger C, van Mol MMC, Hawryluck L, Azoulay E. Ten areas for ICU clinicians to be aware of to help retain nurses in the ICU. Crit Care. 2022 Oct 13;26(1):310. doi: 10.1186/s13054-022-041…
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More Fluids vs. Vasopressors During the First 24 Hours of Septic Shock (CLOVERS Trial)
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19:03Show Notes: eddyjoemd.com/clovers/ TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/Discount code: EDDYJOEMD25 Citation: National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network; Shapiro NI, Douglas IS, Brower RG, Brown SM, Exline MC, Ginde AA, Gong MN, Grissom CK, Hayden …
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Show Notes: eddyjoemd.com/hello-2023/
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Evaluation of patients with Cardiogenic Shock. Why do we need a swan, introduction to CPO, PAPi and survival rates in these critically ill patients Show Notes: https://eddyjoemd.com/cardiogenic-shock-mcs/ TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/Discount code: EDDYJOEMD25
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Evaluation of patients with Cardiogenic Shock. Part two of who knows how many episodes I will create on this topic. In this episode I discuss the stages and prognosis based on the staging. Show Notes: https://eddyjoemd.com/cardiogenic-shock-mcs/ TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/ Discount code: EDDYJOEMD25…
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Evaluation of patients with Cardiogenic Shock. Part one of who knows how many episodes I will create on this topic. Definition, Clinical Manifestations, Phenotypes and an Introduction to Management Strategies Show Notes: https://eddyjoemd.com/cardiogenic-shock-mcs/ TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/ Discount code: EDD…
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Acute Pancreatitis Resuscitation: No Need to Overdo It
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14:53How should we provide IV fluids to patient with acute pancreatitis? Let's look at a recent paper in the NEJM that helps with rate & duration. In this episode, we discuss the resuscitation of acute pancreatitis and why it's important not to overdo it. Acute pancreatitis is a common condition that can be associated with significant morbidity and mort…
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Milrinone vs. Dobutamine in Cardiogenic Shock: Which is Better?
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8:57Should we use milrinone or dobutamine in patients in cardiogenic shock? NEJM published data providing us with the answer. In this episode, we explore the topic of cardiogenic shock and the use of two common medications, milrinone and dobutamine, in treating it. We examine the mechanisms of action, potential side effects, and clinical outcomes assoc…
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Do Cardiogenic Shock Patients Need a Swan-Ganz/Pulmonary Artery Catheter?
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9:23Do Cardiogenic Shock Pts Need a Swan-Ganz/Pulmonary Artery Catheter? Let's look at the data. Let's also look at the devices such as pulse-contour analysis and bioreactance to see if they could replace the PA catheter in the management of cardiogenic shock. Show Notes: https://eddyjoemd.com/cardiogenic-shock-swan/ Mechanical Circulatory Support Note…
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Pulmonary Artery Pulsatility Index (PAPi)
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10:08Pulmonary Artery Pulsatility Index (PAPi) is a hemodynamic parameter with prognostic value in pts w/right heart failure & cardiogenic shock. Show Notes: https://eddyjoemd.com/papi/ Citations: Lim HS, Gustafsson F. Pulmonary artery pulsatility index: physiological basis and clinical application. Eur J Heart Fail. 2020 Jan;22(1):32-38. doi: 10.1002/e…
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Bicarb in Diabetic Ketoacidosis (DKA): Should You Change Your Practice?
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8:28Should we provide our DKA patients with sodium bicarbonate (bicarb) pushes or drips to improve their pH? Let's look at the data. In this episode, we dive into the controversial topic of using bicarbonate in the management of diabetic ketoacidosis (DKA). Is it beneficial or harmful? We review the current evidence and guidelines to help you make info…
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Trust the MAP on the Patient Monitor. Not the SBP nor DBP on Patients with a BP Cuff
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9:32When you're taking one of those automated blood pressure measurements on an oscillometric device, you should trust the MAP. Show Notes: https://eddyjoemd.com/oscillometric-map/
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High-Flow Nasal Oxygen: Clinical Guidelines by the European Respiratory Society
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12:13The European Respiratory Society has provided 8 conditional recommendations for the use of nasal high flow/high flow nasal cannula/high flow oxygen/whatever you want to call it. Here, I review the 8 recommendations and add some commentary on them. Show Notes: https://eddyjoemd.com/high-flow/ Citation: Oczkowski S, Ergan B, Bos L, Chatwin M, Ferrer …
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Is intermittent fasting (time-restricted-eating) with a calorie restriction better than just a calorie restriction? Show Notes: https://eddyjoemd.com/intermittent-fasting/ Citation: Liu D, Huang Y, Huang C, Yang S, Wei X, Zhang P, Guo D, Lin J, Xu B, Li C, He H, He J, Liu S, Shi L, Xue Y, Zhang H. Calorie Restriction with or without Time-Restricted…
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Aspirin in COVID-19: Has It Made a Comeback?
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8:59Aspirin has been thoroughly studied for patients with COVID-19. This study is a positive trial suggesting benefits to using it. But should we? Let's interpret the data given recent advancements. Show Notes: https://eddyjoemd.com/aspirin-covid/ Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, L…
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