Sara Gerkeis an associate professor of law at the University of Illinois Urbana-Champaign. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. S. Gerke, M.B. Jacoby, and I.G. Cohen. Bankruptcy, Genetic Information, and Privacy — Selling Personal Information. N Engl J Med 2025;392:937-939.…

Featuring articles on bacterial vaginosis, diabetes prevention, Danon disease, chronic spontaneous urticaria, and VITT-like monoclonal gammopathy of thrombotic significance; a review article on micronutrients; a Clinical Problem-Solving on unveiling the unforeseen; and Perspectives on bankruptcy and genetic information, on drug development for rare…

In this NEJM Outbreaks Update, Editor-in-Chief Eric Rubin and Deputy Editor Lindsey Baden are joined by veterinarian and virologist Yoshihiro Kawaoka to discuss avian influenza and its current impact on chickens, cows, cats, and humans. Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Yoshihiro Kawa…

John Kelly is the director of the Recovery Research Institute at Massachusetts General Hospital and a professor of psychiatry in addiction medicine at Harvard Medical School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J.F. Kelly, N.D. Volkow, and H.K. Koh. The Changing Approach to Addiction — From Incarcera…

Featuring articles on H5N1 infection, chronic subdural hematoma, achondroplasia, and B-cell acute lymphoblastic leukemia; a review article on carceral health care; a case report of a woman with weakness, back pain, and pancytopenia; and Perspectives on the changing approach to addiction, on the moral injury of inhaler prescribing, and on how one si…

Peter Ubel is a professor of business, public policy, and medicine at Duke University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. P.A. Ubel, A. Grouls, and A.S. Kesselheim. Out of Pocket Getting Out of Hand — Reducing the Financial Toxicity of Rapidly Approved Drugs. N Engl J Med 2025;392:729-731.…

Featuring articles on ventricular tachycardia, chronic lymphocytic leukemia, chronic kidney disease, kidney allografts, and a low-dose yellow fever vaccine; a review article on tubal ectopic pregnancy; a case report of a man with abdominal pain; and Perspectives on reducing the financial toxicity of rapidly approved drugs, on resilience, and on the…

Yashaswini Singh is an assistant professor of health services, policy, and practice at Brown University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. Y. Singh, E. Fuse Brown, and I. Papanicolas. The Rise of Private Equity in Health Care — Not a Uniquely American Phenomenon. N Engl J Med 2025;392:627-629.…

Featuring articles on therapies in acute myocardial infarction and in neuroendocrine tumors, mpox in Africa, and T-cell lymphoma after CAR T-cell therapy; a review article on food and nutrition insecurity; a case report of a woman with headache and dysesthesia; and Perspectives on Marburg virus disease in Rwanda, on the rise of private equity in he…

We're back, after a brief hiatus! Today we talk about duration of therapy for bacteremia, Factor XI inhibition for atrial fibrillation, whether to stop ACEi or ARB before elective surgery, and whether GLP-1 agonists are beneficial in heart failure with preserved ejection fraction. Go to minute 7:30 to skip the banter. 7 vs 14 Days of Antibiotics fo…

Joseph Ross is a professor in the Department of Internal Medicine at the Yale School of Medicine and in the Department of Health Policy and Management at the Yale School of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J.S. Ross. Cell and Gene Therapies — Improving Access and Outcomes for Medica…

Featuring articles on IgA nephropathy, a treatment in children with obesity, NRG1 fusion–positive cancer, a case of a T-cell lymphoma, and the discovery of GLP-1–based drugs; a review article on hemophagocytic lymphohistiocytosis, a Clinical Problem-Solving on traveling companions; and Perspectives on cell and gene therapies, on gender-affirming ca…

Daniel Aaron is an associate professor of law at the University of Utah S.J. Quinney College of Law. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D.G. Aaron and C. Robertson. E-Cigarettes at the Supreme Court — Potential Implications for the FDA and Public Health. N Engl J Med 2025;392:417-419.…

Featuring articles on heart failure and obesity, oral anticoagulation during TAVI, hemophilia A, hereditary angioedema, and tuberculosis; a review article on sport-related concussion; a case report of a man with syncope, ankle swelling, and abnormal chest imaging; and Perspectives on e-cigarettes at the Supreme Court, on providing interstate telehe…

This discussion highlights the importance of recognizing that everyone can engage in leading within their roles, while also addressing the crucial skills of followership and the need for clarity in leadership roles to foster effective teamwork and improve patient outcomes.By James Mountford, Thomas H. Lee

How hospitals are facilitating knowledge sharing and accelerating the implementation of value-based health care with Value Catalyst.By Paul B. van der Nat, Thomas H. Lee

Craig Spencer is an emergency medicine physician and an associate professor of the practice of health services, policy, and practice at the Brown University School of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. C. Spencer. Ebola and a Decade of Disparities — Forging a Future for Global Health …

Featuring articles on esophageal cancer, out-of-hospital cardiac arrest, and atrial fibrillation; a review article on the physiology of hunger; a case report of a man with exertional dyspnea and chest pain; a Medicine and Society on evaluating the inclusion of sex in clinical algorithms; and Perspectives on Ebola, on U.S. generic drug shortages, on…

Carmel Shachar is an assistant clinical professor of law and faculty director of the Health Law and Policy Clinic at Harvard Law School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. T. Ramesh, C. Shachar, and H. Yu. Striking a Balance — Advancing Physician Collective-Bargaining Rights and Patient Protections.…

Featuring articles on asymptomatic severe aortic stenosis, kidney disease, fracture prevention in women, and residual breast cancer, the future of the U.S. physician workforce, mutant KRAS signaling, and manufactured chemicals and children’s health; a review article on the identification and treatment of alcohol use disorder; a case report of a man…

David Velasquez is an internal medicine resident physician at Brigham and Women's Hospital. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D.E. Velasquez, E.T. Roberts, and J.F. Figueroa. The Plight of “Dual Noneligible” People in the United States. N Engl J Med 2025;392:105-107.…

Featuring articles on transcatheter tricuspid-valve replacement, persistent chylomicronemia, multiple myeloma, myelofibrosis, and peripherally inserted central catheter materials; a review article on heart failure with preserved ejection fraction; a case report of a woman with shortness of breath and leg edema; and Perspectives on the plight of “du…

What are the key health care policy challenges and opportunities on the horizon for 2025, and how might recent election outcomes shape these discussions?By Mark McClellan, Edward Prewitt

Joey Mattingly is an associate professor in the Department of Pharmacotherapy at the University of Utah College of Pharmacy. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. S.S. Tu, S. Kottilil, and T.J. Mattingly II. Leveraging Old Hepatitis C Therapies. N Engl J Med 2025;392:1-4.…

Featuring articles on advanced melanoma, atrial fibrillation, ATTR amyloidosis, and bladder cancer; a review article on cervical cancer; a Clinical Problem-Solving describing when blurry vision clouds the bigger picture; Medicine and Society’s on transitional justice and on rethinking access to HIV medicines; and Perspectives on hepatitis C therapi…

Lauren Schiff is an associate professor of Ob/Gyn and a minimally invasive gynecologic surgeon at the University of North Carolina School of Medicine and the associate chief medical officer for quality and safety at UNC Hospitals. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. L.D. Schiff, A.O.D. Hester, and T.…

Featuring articles on cancer cachexia, MDR tuberculosis, Ebola virus disease, and severe asthma; a review article on the nonsurgical management of chronic venous insufficiency; a case report of a woman with end-stage liver disease and headache; and Perspectives on providing effective medical care to autistic people, on independent physician associa…